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BRAIN is an European leader in white (industrial) biotechnology.BRAIN provides innovative solutions from natural biodiversity for successful applications in the chemical, pharmaceutical, cosmetics and food industries. In an unique approach to the identification and production of new recombinant compounds, enzymes and biocatalysts it applies advanced technologies of molecular biology to exploit the untapped biodiversity. The company’s success is centred around its proprietary BioArchive comprising millions of genes of as yet uncultivable microorganisms as well as microbial isolates. BRAIN utilises its exceptional resources and technical expertise to develop specific new candidate molecules for the pharmaceutical and cosmetics market and enzymes with predefined properties for the chemical and life science industry. BRAIN activities range from contract services in molecular biology to fully-fledged research and development collaborations. As a discovery-development interface the company performs projects through all phases from discovery to the establishment of optimised production protocols. In addition, in-house research programs are pursued to develop antibiotics and bioactive candidates and to build up a proprietary collection of enzymes for industrial applications. BRAIN turns biodiversity into an accessible source of biomolecules for the development of bioactives and enzymes. Its EvoSolution® discovery platform combines validated technologies and unique resources with creative strategies for assay development and lead optimisation. Its BioArchive combines a comprehensive collection of molecularly characterised microorganisms stored in a way that allows immediate screening for metabolites or biocatalysts, and an ever-growing number of “metagenome” libraries. This large cloned DNA fragments represent the genomes of entire communities of microorganisms of which typically up to 99 percent are non-cultivable. Presently estimated at some 140 million genes, these libraries encode a wealth of enzymes and entire metabolic pathways. Based on its technologies and resources BRAIN designs and executes custom-made projects to find the right solution for a specific application. BRAIN’s multidisciplinary team of scientists and technicians combine profound expertise in molecular genetics, protein chemistry, microbiology and cell biology. Long-standing collaborations with renowned research laboratories and academic centres in Europe and overseas ensure a constant flow of know-how and access to new resources. Founded in 1993 as a privately owned and independent research corporation, BRAIN provides validated R&D technologies and screening resources to the life science industry. In 1998 the company received an award for its innovative scientific concept.
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